Fluorescent indicators based on BODIPY

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2012 English Publisher:Royal Society of Chemistry (RSC)Journal:Chem. Soc. Rev., volume 41, pages 1,130-1,172 (issn: 0306-0012, eissn: 1460-4744,

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Authors: Noël, Boens; Volker, Leen; Wim, Dehaen;

doi: 10.1039/c1cs15132k

pmid: 21796324

Fluorescent indicators based on BODIPY

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Abstract

This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent indicators for pH, metal ions, anions, biomolecules, reactive oxygen species, reactive nitrogen species, redox potential, chemical reactions and various physical phenomena. The sections of the review describing the criteria for rational design of fluorescent indicators and the mathematical expressions for analyzing spectrophotometric and fluorometric titrations are applicable to all fluorescent probes (206 references).

Related Organizations

KU Leuven
Belgium
Katholieke Universiteit Leuven
Belgium

Keywords

Boron Compounds, Chemical Phenomena, Drug Design, Animals, Humans, Fluorescent Dyes

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