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Chemical Communications
Article
Data sources: UnpayWall
Chemical Communications
Article . 2010 . Peer-reviewed
Data sources: Crossref
Chemical Communications
Article . 2010
Data sources: Europe PubMed Central
https://dx.doi.org/10.1039/b92...
Article
Data sources: Microsoft Academic Graph
https://dx.doi.org/10.1039/b92...
Article
Data sources: Microsoft Academic Graph
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Enzymatic activation of a matrix metalloproteinase inhibitor

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2010 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 46, page 1,241 (issn: 1359-7345, eissn: 1364-548X, Copyright policy )
Authors: Jody L, Major Jourden; Seth M, Cohen;

doi: 10.1039/b923302d

pmid: 20449263

pmc: PMC2867072

Enzymatic activation of a matrix metalloproteinase inhibitor

Abstract

Matrix metalloproteinase inhibitors (MMPi) possessing a glucose protecting group on the zinc-binding group (ZBG) show a dramatic increase in inhibitory activity upon cleavage by beta-glucosidase.

Related Organizations
Keywords

Molecular Structure, beta-Glucosidase, Prodrugs, Protease Inhibitors, Matrix Metalloproteinase Inhibitors, Matrix Metalloproteinases

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 11
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Top 10%
Top 10%
bronze