Molecularly imprinted cavities template the macrocyclization of tetrapeptides

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2008 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications (issn: 1359-7345, eissn: 1364-548X,

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Authors: Dar-Fu, Tai; Yee-Fung, Lin;

doi: 10.1039/b813439a

pmid: 18997964

Molecularly imprinted cavities template the macrocyclization of tetrapeptides

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Abstract

Cavities formed using cyclic tetrapeptides (CTPs) or heat-induced conformers act as templates for cyclization; the cavities bind to linear tetrapeptides and enforce turn conformations to enhance cyclization to constrained CTPs.

Related Organizations

National Dong Hwa University
Taiwan

Keywords

Molecular Imprinting, Hot Temperature, Molecular Structure, Cyclization, Oligopeptides

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