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Duration of untreated bipolar disorder: a multicenter study

مدة الاضطراب الثنائي القطب غير المعالج: دراسة متعددة المراكز
Authors: Ling Zhang; Xinguang Yu; Yi Fang; Gábor S. Ungvári; Chee H. Ng; Helen Chiu; Hui Chun Li; +5 Authors

Duration of untreated bipolar disorder: a multicenter study

Abstract

AbstractLittle is known about the demographic and clinical differences between short and long duration of untreated bipolar disorder (DUB) in Chinese patients. This study examined the demographic and clinical features of short (≤2 years) and long DUB (>2 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) was examined in 7 psychiatric hospitals and general hospital psychiatric units across China. Patients’ demographic and clinical characteristics were collected using a standardized protocol and data collection procedure. The mean DUB was 3.2 ± 6.0 years; long DUB accounted for 31.0% of the sample. Multivariate analyses revealed that longer duration of illness, diagnosis of BD type II, and earlier misdiagnosis of BD for major depressive disorder or schizophrenia were independently associated with long DUB. The mean DUB in Chinese BD patients was shorter than the reported figures from Western countries. The long-term impact of DUB on the outcome of BD is warranted.

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Australia
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Keywords

Adult, Male, China, Bipolar Disorder, Time Factors, Adolescent, Bipolar disorder, Bipolar Spectrum Disorder, 150, 610, Social Sciences, Major depressive disorder, Pediatrics, Article, outcomes research, Young Adult, Sociology, Health Sciences, Mood, Medicine and Health Sciences, Odds Ratio, Humans, Psychology, Bipolar I disorder, Obsessive-Compulsive Disorder and Related Conditions, Internal medicine, Demography, bipolar disorder, Psychiatry, Schizophrenia (object-oriented programming), Middle Aged, FOS: Sociology, Schizophrenia Research and Treatment, FOS: Psychology, Psychiatry and Mental health, Clinical Psychology, Mania, Cross-Sectional Studies, Epidemiology and Management of Bipolar Disorder, Multivariate analysis, Disease Progression, Medicine, Female, Symptom Assessment

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
24
Top 10%
Top 10%
Top 10%
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