In these last years, there has been a proliferation of new textbooks and of new editions of classical textbooks on medical genetics targeted at medical students. However, these books are all over 400 pages with increasingly complex explanations of new discoveries and concepts. Thus, there is a need, in the field, for a book with shorter length providing the basic information in a comprehensible and digestible manner. This new book, at just under 300 pages, from a long established author and teacher of medical genetics is reaching this goal.