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Communications Biology
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Communications Biology
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Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging

descriptionPublicationkeyboard_double_arrow_right Article , Conference object 06 Mar 2024 United States English Publisher:Springer Science and Business Media LLCJournal:Communications Biology, volume 7 (eissn: 2399-3642, Copyright policy )Funded by:NIH | High throughput optical c..., NIH | High-throughput integrate...
Authors: Chao Ren; Senyue Hao; Fei Wang; Abigail Matt; Marcello Magri Amaral; Daniel Yang; Leyao Wang; +1 Authors

doi: 10.1038/s42003-024-05973-5

pmid: 38448627

pmc: PMC10918170

Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging

Abstract

AbstractDynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non-invasive label-free volumetric live cell imaging. In this mini review, we explain the core concepts behind DyC-OCT image formation and its system configurations, serving as practical guidance for future DyC-OCT users. Subsequently, we explore its applications in delivering high-quality, contrast-enhanced images of cellular morphology, as well as in monitoring changes in cellular activity/viability assay experiments.

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United States
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Keywords

Optical Coherence, QH301-705.5, Cell Survival, Mini Review, ICTS (Institute of Clinical and Translational Sciences), Medicine and Health Sciences, Biology (General), Tomography, Tomography, Optical Coherence

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
34
Top 10%
Top 10%
Top 1%
Green
gold