A picture of Mitf in melanoma immortality

descriptionPublicationkeyboard_double_arrow_right Article 31 Jan 2011 English Publisher:Springer Science and Business Media LLCJournal:Oncogene, volume 30, pages 2,304-2,306 (issn: 0950-9232, eissn: 1476-5594,

Copyright policy )

Authors: C R Goding;

doi: 10.1038/onc.2010.641

A picture of Mitf in melanoma immortality

- Summary
- Metrics

Abstract

The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis.

Related Organizations

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	60
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%