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Nature Structural & Molecular Biology
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Nature Structural & Molecular Biology
Article . 2016 . Peer-reviewed
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Nature Structural & Molecular Biology
Article . 2016
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https://dx.doi.org/10.1038/nsm...
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http://dx.doi.org/10.1038/nsmb...
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The mystery of the fusion pore

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2016 English Publisher:Springer Science and Business Media LLCJournal:Nature Structural & Molecular Biology, volume 23, pages 5-6 (issn: 1545-9993, eissn: 1545-9985, Copyright policy )Funded by:NIH | Time superresolution micr..., EC | THE FUSION MACHINE
Authors: Satyan Sharma; Manfred Lindau;

doi: 10.1038/nsmb.3157

pmid: 26733219

pmc: PMC4910880

handle: 11858/00-001M-0000-0029-7F70-F , 11858/00-001M-0000-0029-61A4-7 , 11858/00-001M-0000-0029-61A6-3

The mystery of the fusion pore

Abstract

Release of neurotransmitters occurs by opening of a fusion pore in a manner thought to be mediated by SNARE proteins, but whether the fusion pore is a lipidic or a proteinaceous structure is controversial. A new study using very small nanodiscs shows that it is both.

Related Organizations
Keywords

Secretory Vesicles, Lipid Bilayers, Animals, SNARE Proteins, Membrane Fusion, Exocytosis

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 16
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
16
Average
Average
Top 10%
bronze