
doi: 10.1038/nrmicro888
pmid: 15100696
Antibiotic resistance is thought to evolve rapidly in response to antibiotic use. At present, we lack effective tools to assess how rapidly existing resistance genes are likely to evolve to yield resistance to newly introduced drugs. To address this problem, a method has been developed for in vitro evolution experiments to help predict how long it will take antibiotic resistance to arise — potentially allowing informed decisions about usage to be made.
Drug Resistance, Multiple, Bacterial, Animals, Humans, Bacterial Infections, Directed Molecular Evolution, Selection, Genetic, Anti-Bacterial Agents
Drug Resistance, Multiple, Bacterial, Animals, Humans, Bacterial Infections, Directed Molecular Evolution, Selection, Genetic, Anti-Bacterial Agents
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