Highway to the inner nuclear membrane: rules for the road
Copyright policy )Highway to the inner nuclear membrane: rules for the road
To enter the nucleus a protein must be chaperoned by a transport factor through the nuclear pore complex or it must be small enough to pass through by diffusion. Although these principles have long described the nuclear import of soluble proteins, recent evidence indicates that they also apply to the import of integral inner nuclear membrane proteins. Here we develop a set of rules that might govern the transport of proteins to the inner nuclear membrane.
- Rockefeller University United States
- Howard Hughes Medical Institute United States
Cell Nucleus, Nuclear Envelope, Nuclear Localization Signals, Active Transport, Cell Nucleus, Karyopherins, Models, Biological, Nuclear Pore Complex Proteins, Protein Transport, Nuclear Pore, Animals, Humans
Cell Nucleus, Nuclear Envelope, Nuclear Localization Signals, Active Transport, Cell Nucleus, Karyopherins, Models, Biological, Nuclear Pore Complex Proteins, Protein Transport, Nuclear Pore, Animals, Humans
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