Combinatorial microscopy

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2006 English Publisher:Springer Science and Business Media LLCJournal:Nature Reviews Molecular Cell Biology, volume 7, pages 944-952 (issn: 1471-0072, eissn: 1471-0080,

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Authors: Daniel, Axelrod; Geneva M, Omann;

doi: 10.1038/nrm2062

pmid: 17139334

Combinatorial microscopy

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Abstract

By taking advantage of combinations of the many rich properties of photons, new forms of optical microscopy can now be used to visualize features of samples beyond thickness and density variations. We are now within reach of viewing the motions, orientations, binding kinetics and specific transient associations of previously 'submicroscopic' cellular structures and single molecules.

Related Organizations

University of Michigan–Flint
United States

Keywords

Microscopy, Photons, Microscopy, Fluorescence, Neutrophils, Fluorescence Resonance Energy Transfer, Animals, Humans, Surface Plasmon Resonance, Sensitivity and Specificity, Fluorescence Recovery After Photobleaching

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