
doi: 10.1038/nrm1716
pmid: 16231420
The focus of developmental biologists has expanded from the analysis of gene expression to include the analysis of cell signalling. Heterotrimeric G proteins (G proteins) mediate signalling from a superfamily of heptahelical receptors (G-protein-coupled receptors) to a smaller number of effector units that include adenylyl cyclases, phospholipase C and various ion channels. The convergence of developmental biology with cell signalling has now revealed overlaps in which G proteins mediate complex pathways in embryonic development.
Protein Subunits, GTP-Binding Proteins, Morphogenesis, Animals, Humans, Models, Biological, Second Messenger Systems, Developmental Biology, Receptors, G-Protein-Coupled
Protein Subunits, GTP-Binding Proteins, Morphogenesis, Animals, Humans, Models, Biological, Second Messenger Systems, Developmental Biology, Receptors, G-Protein-Coupled
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