Mitochondrial fission in apoptosis

descriptionPublicationkeyboard_double_arrow_right Article 15 Jul 2005 English Publisher:Springer Science and Business Media LLCJournal:Nature Reviews Molecular Cell Biology, volume 6, pages 657-663 (issn: 1471-0072, eissn: 1471-0080,

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Authors: Richard J, Youle; Mariusz, Karbowski;

doi: 10.1038/nrm1697

pmid: 16025099

Mitochondrial fission in apoptosis

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Abstract

Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.

Related Organizations

National Institutes of Health
United States
National Institute of Health
Pakistan
National Institute of Neurological Disorders and Stroke
United States

Keywords

Mitochondrial Proteins, Animals, Humans, Apoptosis, Microtubule-Associated Proteins, Mitochondria

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