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Nature Reviews Molecular Cell Biology
Article . 2017 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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Charting the unknown epitranscriptome

Authors: Novoa Pardo, EM; Mason, CE; Mattick, JS;

Charting the unknown epitranscriptome

Abstract

RNA modifications can alter RNA structure-function relationships and various cellular processes. However, the genomic distribution and biological roles of most RNA modifications remain uncharacterized. Here, we propose using phage display antibody technology and direct sequencing through nanopores to facilitate systematic interrogation of the distribution, location and dynamics of RNA modifications.

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Australia
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Keywords

RNA Processing, 570, anzsrc-for: 42 Health sciences, Post-Transcriptional, 3102 Bioinformatics and Computational Biology, anzsrc-for: 32 Biomedical and clinical sciences, anzsrc-for: 11 Medical and Health Sciences, 616, Genetics, anzsrc-for: 06 Biological Sciences, Animals, Humans, RNA, anzsrc-for: 31 Biological Sciences, anzsrc-for: 3102 Bioinformatics and Computational Biology, RNA Processing, Post-Transcriptional, Cell Surface Display Techniques, Transcriptome, 31 Biological Sciences

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    52
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
52
Top 10%
Top 10%
Top 10%
Green