
doi: 10.1038/nrd1728
pmid: 15962524
Cetuximab (Erbitux; ImClone Systems/Bristol-Myers Squibb) is a monoclonal antibody that binds to the epidermal growth factor receptor, which is important in the growth of many cancers. In February 2004, it was granted accelerated approval by the US FDA for the treatment of metastatic colorectal cancer on the basis of tumour response rates in Phase II trials.
ErbB Receptors, Clinical Trials as Topic, Treatment Outcome, Antibodies, Monoclonal, Cetuximab, Humans, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Colorectal Neoplasms, Signal Transduction
ErbB Receptors, Clinical Trials as Topic, Treatment Outcome, Antibodies, Monoclonal, Cetuximab, Humans, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Colorectal Neoplasms, Signal Transduction
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
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