NUB1 snubs huntingtin toxicity
Copyright policy )NUB1 snubs huntingtin toxicity
A screen now identifies a protein that regulates degradation of mutant huntingtin, which causes Huntington's disease, and manipulations show that promoting clearance of the toxic protein itself may be sufficient to halt disease.
- University of California, San Francisco United States
- Gladstone Institutes United States
Male, Neurons, Huntingtin Protein, Neurology & Neurosurgery, Biomedical and Clinical Sciences, Biological Psychology, Neurosciences, Signal Transducing, Adaptor Proteins, Nerve Tissue Proteins, Pregnancy, Mutation, Psychology, Biological psychology, Animals, Humans, Cognitive Sciences, Female, Adaptor Proteins, Signal Transducing, Transcription Factors
Male, Neurons, Huntingtin Protein, Neurology & Neurosurgery, Biomedical and Clinical Sciences, Biological Psychology, Neurosciences, Signal Transducing, Adaptor Proteins, Nerve Tissue Proteins, Pregnancy, Mutation, Psychology, Biological psychology, Animals, Humans, Cognitive Sciences, Female, Adaptor Proteins, Signal Transducing, Transcription Factors
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