A synthetic approach to abiogenesis

descriptionPublicationkeyboard_double_arrow_right Article 29 Apr 2014 English Publisher:Springer Science and Business Media LLCJournal:Nature Methods, volume 11, pages 495-498 (issn: 1548-7091, eissn: 1548-7105,

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Authors: James, Attwater; Philipp, Holliger;

doi: 10.1038/nmeth.2893

pmid: 24781322

A synthetic approach to abiogenesis

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Abstract

Synthetic biology seeks to probe fundamental aspects of biological form and function by construction (resynthesis) rather than deconstruction (analysis). Here we discuss how such an approach could be applied to assemble synthetic quasibiological systems able to replicate and evolve, illuminating universal properties of life and the search for its origins.

Related Organizations

Medical Research Council
United Kingdom
MRC Laboratory of Molecular Biology
United Kingdom

Keywords

DNA Replication, Genome, Bacteria, DNA, Evolution, Molecular, Phenotype, Genetic Techniques, Metabolic Engineering, Research Design, RNA, Synthetic Biology, Genetic Engineering, Software

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