Capturing condensin in chromosomes

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2017 English Publisher:Springer Science and Business Media LLCJournal:Nature Genetics, volume 49, pages 1,419-1,420 (issn: 1061-4036, eissn: 1546-1718,

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Authors: Tatsuya, Hirano;

doi: 10.1038/ng.3962

pmid: 28951628

Capturing condensin in chromosomes

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Abstract

A new study uses a Hi-C technique to demonstrate that condensin has a major role in remodeling interphase chromatin into mitotic chromosomes. This study provides insight into the mechanism whereby a centimeters-long DNA molecule is folded into a micrometers-long rod-shaped chromosome.

Related Organizations

RIKEN
Japan

Keywords

Adenosine Triphosphatases, DNA-Binding Proteins, Multiprotein Complexes, Mitosis, Chromosomes

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