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</script>doi: 10.1038/nchembio848
pmid: 17173028
Though they started out as somewhat mysterious components of the RNAi effector complexes, Argonaute proteins have since taken center stage in RNAi gene silencing. They interact with small RNAs to effect gene silencing in all RNAi-related pathways known so far. We will review the dramatic advances in our understanding of the role of the Argonautes in RNAi through studies of their structure and function.
Models, Molecular, Ribonuclease III, Protein Structure, Tertiary, Pyrococcus furiosus, Peptide Initiation Factors, Animals, Humans, RNA Interference, Amino Acid Sequence, Schizosaccharomyces pombe Proteins, RNA Processing, Post-Transcriptional, Sequence Alignment, Signal Transduction
Models, Molecular, Ribonuclease III, Protein Structure, Tertiary, Pyrococcus furiosus, Peptide Initiation Factors, Animals, Humans, RNA Interference, Amino Acid Sequence, Schizosaccharomyces pombe Proteins, RNA Processing, Post-Transcriptional, Sequence Alignment, Signal Transduction
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