Name: Click chemistry gets reversible
Creator: Fulton DA
Keywords: Dioxanes, Water, Click Chemistry, 02 engineering and technology, Sulfhydryl Compounds, Amines, Hydrogen-Ion Concentration, 0210 nano-technology, 01 natural sciences, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 22 Sep 2016 English Publisher:Springer Science and Business Media LLCJournal:Nature Chemistry, volume 8, pages 899-900 (issn: 1755-4330, eissn: 1755-4349,

Authors: Fulton DA;

doi: 10.1038/nchem.2626

pmid: 27657860

Click chemistry gets reversible

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Abstract

'Click' chemistry allows for the linking together of chemical modules, however, there are currently no methods that also allow for facile 'declicking' to unlink them. Now, a method has been developed to click together amines and thiols, and then allow a chemically triggered declick reaction to release the original molecular components.

Related Organizations

Newcastle University
United Kingdom

Keywords

Dioxanes, Water, Click Chemistry, Sulfhydryl Compounds, Amines, Hydrogen-Ion Concentration

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