Clarifying the role of condensin in shaping chromosomes
Copyright policy )Clarifying the role of condensin in shaping chromosomes
A major controversy in the field of chromosome research has been whether condensin is required for achieving the highly compacted state of chromatin fibres in mitosis and meiosis. Through genetic experiments in mouse oocytes, condensin is now found to be indispensable for meiotic chromosome assembly by mediating chromosome compaction and disentanglement of sister chromatids and by conferring rigidity to chromosomes.
Adenosine Triphosphatases, DNA-Binding Proteins, Meiosis, Chromosomal Proteins, Non-Histone, Chromosome Segregation, Multiprotein Complexes, Animals, Nuclear Proteins, Cell Cycle Proteins
Adenosine Triphosphatases, DNA-Binding Proteins, Meiosis, Chromosomal Proteins, Non-Histone, Chromosome Segregation, Multiprotein Complexes, Animals, Nuclear Proteins, Cell Cycle Proteins
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