Hippo signalling directs intestinal fate
Copyright policy )Hippo signalling directs intestinal fate
Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo signalling, YAP and TAZ1. These are now shown to have a dual role in the intestinal epithelium, regulating both stem cell proliferation and differentiation along a specific secretory lineage.
- University of Copenhagen Denmark
- University of Copenhagen Denmark
- University of Copenhagen Denmark
Male, Stem Cells, Cell Cycle Proteins, YAP-Signaling Proteins, Phosphoproteins, Animals, Goblet Cells, Intestinal Mucosa, Acyltransferases, Adaptor Proteins, Signal Transducing, Transcription Factors
Male, Stem Cells, Cell Cycle Proteins, YAP-Signaling Proteins, Phosphoproteins, Animals, Goblet Cells, Intestinal Mucosa, Acyltransferases, Adaptor Proteins, Signal Transducing, Transcription Factors
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