Multiple modes of cytoplasmic dynein regulation
Copyright policy )Multiple modes of cytoplasmic dynein regulation
In performing its multiple cellular functions, the cytoplasmic dynein motor is subject to complex regulation involving allosteric mechanisms within the dynein complex, as well as numerous extramolecular interactions controlling subcellular targeting and motor activity. Recent work has distinguished high- and low-load regulatory modes for cytoplasmic dynein, which, combined with a diversity of targeting mechanisms, accounts for a very broad range of functions.
- University of California, San Francisco United States
- Columbia University United States
- King’s University United States
Cytoplasmic Dyneins, Biological Transport, Dynactin Complex, Models, Biological, 1-Alkyl-2-acetylglycerophosphocholine Esterase, Animals, Humans, Protein Multimerization, Carrier Proteins, Microtubule-Associated Proteins, Protein Binding
Cytoplasmic Dyneins, Biological Transport, Dynactin Complex, Models, Biological, 1-Alkyl-2-acetylglycerophosphocholine Esterase, Animals, Humans, Protein Multimerization, Carrier Proteins, Microtubule-Associated Proteins, Protein Binding
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