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doi: 10.1038/ncb0210-106
pmid: 20118997
Separation of sister chromatids at anaphase in metazoan cells requires only the cleavage of the kleisin subunit of centromeric cohesin, but efficient poleward movement of separated sisters requires the associated loss in Cdk1 activity. Activation of the anaphase-promoting complex/cyclosome ensures these events are coordinated.
570, Chromosomal Proteins, Non-Histone, 500, Ubiquitin-Protein Ligase Complexes, Cell Cycle Proteins, Chromatids, Models, Biological, Anaphase-Promoting Complex-Cyclosome, CDC2 Protein Kinase, Animals, Humans, Anaphase, Cohesins
570, Chromosomal Proteins, Non-Histone, 500, Ubiquitin-Protein Ligase Complexes, Cell Cycle Proteins, Chromatids, Models, Biological, Anaphase-Promoting Complex-Cyclosome, CDC2 Protein Kinase, Animals, Humans, Anaphase, Cohesins
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