Limits to lifespan

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2002 English Publisher:Springer Science and Business Media LLCJournal:Nature Cell Biology, volume 4, pages E25-E27 (issn: 1465-7392, eissn: 1476-4679,

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Authors: Alison C, Lloyd;

doi: 10.1038/ncb0202-e25

pmid: 11835050

Limits to lifespan

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Abstract

It has long-been accepted that normal somatic cells have intrinsic mechanisms that limit their proliferative lifespan. Recent work has now challenged this view by demonstrating that extrinsic factors might be determining proliferative potential.

Related Organizations

University College London
United Kingdom

Keywords

Phenotype, Cell Culture Techniques, Animals, Humans, Fibroblasts, Telomerase, Cell Division, Cells, Cultured, Cellular Senescence, Signal Transduction

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