Renal vitamin D receptor expression and vitamin D renoprotection

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2012 English Publisher:Elsevier BVJournal:Kidney International, volume 81, pages 937-939 (issn: 0085-2538,

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Authors: Dusso, Adriana S.;

doi: 10.1038/ki.2012.30

pmid: 22543902

Renal vitamin D receptor expression and vitamin D renoprotection

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Abstract

Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.

Related Organizations

University of Lleida (UdL)
Spain
University of Lleida
Spain
Biomedical Research Institute
United States
Biomedical Research Institute of Lleida
Spain

Keywords

Male, Fibroblast Growth Factor-23, Nephrology, Animals, Humans, Receptors, Calcitriol, Female, Kidney

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