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Kidney International
Article . 1992
License: Elsevier Non-Commercial
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Platelet-derived growth factor receptors and phospholipase C activation

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1992Publisher:Elsevier BVJournal:Kidney International, volume 41, pages 575-580 (issn: 0085-2538, Copyright policy )
Authors: Thomas O. Daniel; Dana A. Kumjian;

doi: 10.1038/ki.1992.85

pmid: 1315404

Platelet-derived growth factor receptors and phospholipase C activation

Abstract

Platelet-derived growth factor (PDGF) has been assigned a broad range of biological roles in contexts ranging from development and oncogenesis to wound healing and atherogenesis [1]. Originally assayed as mitogenic activity released from platelets, it is now appreciated that, in addition to its proliferative actions, PDGF stimulates other processes including chemoattraction, deposition of extracellular matrix and neuronotropism. All these biological activies are mediated through transmembrane cell surface tyrosine kinase receptors.

Related Organizations
Keywords

Enzyme Activation, Platelet-Derived Growth Factor, Molecular Structure, Nephrology, Type C Phospholipases, Animals, Tyrosine, Receptors, Cell Surface, Receptors, Platelet-Derived Growth Factor, Phosphorylation

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    		 8
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
8
Average
Average
Top 10%
hybrid