The results of 99 second grafts in individual eyes are reported. The five-year survival of these grafts was 49%. Allograft rejection was responsible for the majority of failures, but recurrence of host disease and endothelial decompensation were also important. Glaucoma was an important complication in 38% of eyes. Only 12 eyes in the series had no significant complication and 18 eyes achieved a corrected visual acuity of 6/12 or better.