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Apoptosis: it's BAK to VDAC

descriptionPublicationkeyboard_double_arrow_right Article 13 Nov 2009 English Publisher:Springer Science and Business Media LLCJournal:EMBO reports, volume 10, pages 1,311-1,313 (issn: 1469-221X, eissn: 1469-3178, Copyright policy )
Authors: Gordon C, Shore;

doi: 10.1038/embor.2009.249

pmid: 19949413

pmc: PMC2799210

Apoptosis: it's BAK to VDAC

Abstract

VDAC's role in Bak‐dependent mitochondrial outer membrane permeabilization (MOMP) is controversial. Gordon Shore makes sense of it all in light of an EMBO reports paper that shows that VDAC mediates mitochondrial recruitment of Bak, thereby controlling tBid‐induced MOMP.

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Keywords

bcl-2 Homologous Antagonist-Killer Protein, Mitochondrial Membranes, Animals, Humans, Voltage-Dependent Anion Channels, Apoptosis, Models, Biological, Permeability, bcl-2-Associated X Protein

  • BIP!
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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 26
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
26
Top 10%
Average
Top 10%
gold
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