Transcriptional speed bumps revealed in high resolution

descriptionPublicationkeyboard_double_arrow_right Article 22 Aug 2018 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 560, pages 560-561 (issn: 0028-0836, eissn: 1476-4687,

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Authors: Karen, Adelman; Telmo, Henriques;

doi: 10.1038/d41586-018-05971-8

pmid: 30143755

Transcriptional speed bumps revealed in high resolution

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Abstract

The enzyme RNA polymerase II, which transcribes DNA, pauses early in transcription and awaits signals to continue. High-resolution structures reveal how it is stopped and efficiently restarted. High-resolution structures of paused and active RNA polymerase II.

Related Organizations

Harvard University
United States

Keywords

RNA Polymerase II

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