descriptionPublicationkeyboard_double_arrow_right Article 23 Feb 2016 English Publisher:Springer Science and Business Media LLCJournal:Cell Research, volume 26, pages 397-398 (issn: 1001-0602, eissn: 1748-7838,

Authors: Stephen C. West; Kasper Fugger;

doi: 10.1038/cr.2016.25

pmid: 26902288

pmc: PMC4822126

Keeping homologous recombination in check

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Abstract

Pathway choice is a critical event in the repair of DNA double-strand breaks. In a recent paper published in Nature, Orthwein et al. define a mechanism by which homologous recombination is controlled in G1 cells to favor non-homologous end joining.

Related Organizations

The Francis Crick Institute
United Kingdom

Keywords

G1 Phase, Humans, Homologous Recombination

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