
Allergic asthma is an inflammatory disease of the airways in which epithelial cells, dendritic cells and innate lymphoid cells are increasingly implicated. Recent findings suggest that apoptotic cells are phagocytosed by airway epithelial cells in a Rac1-dependent manner and this leads to dampening of innate and adaptive immunity to allergens.
rac1 GTP-Binding Protein, Phagocytes, Interleukins, Apoptosis, Epithelial Cells, Dendritic Cells, Allergens, EMC MM-04-42-02, Interleukin-33, Asthma, Interleukin-10, Th2 Cells, Transforming Growth Factor beta, Humans
rac1 GTP-Binding Protein, Phagocytes, Interleukins, Apoptosis, Epithelial Cells, Dendritic Cells, Allergens, EMC MM-04-42-02, Interleukin-33, Asthma, Interleukin-10, Th2 Cells, Transforming Growth Factor beta, Humans
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