Mechanisms Involved in Placebo and Nocebo Responses and Implications for Drug Trials
Copyright policy )Mechanisms Involved in Placebo and Nocebo Responses and Implications for Drug Trials
Drug trials often compare active drugs with inert placebos under double-blind conditions. This standard design is increasingly being questioned in light of recent progress in understanding the mechanisms behind the placebo response.1,2 The growing knowledge of the neurobiology of placebo is forcing us to reconsider the significance of the placebo in clinical practice, with consequent profound implications for the design of clinical trials. Clinical Pharmacology & Therapeutics (2011); 90 5, 722–726. doi:10.1038/clpt.2011.204
- Universität Hamburg Germany
- University of Duisburg-Essen Germany
- Essen University Hospital Germany
- University Medical Center Hamburg-Eppendorf Germany
- Philipps-University of Marburg Germany
Placebos, Double-Blind Method, Pharmaceutical Preparations, Research Subjects, Medizin, Humans, Controlled Clinical Trials as Topic, Placebo Effect
Placebos, Double-Blind Method, Pharmaceutical Preparations, Research Subjects, Medizin, Humans, Controlled Clinical Trials as Topic, Placebo Effect
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