Tailoring vectors through DNA shuffling

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2000 English Publisher:Springer Science and Business Media LLCJournal:Nature Genetics, volume 25, pages 366-367 (issn: 1061-4036, eissn: 1546-1718,

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Authors: David T Curiel;

doi: 10.1038/78023

Tailoring vectors through DNA shuffling

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Abstract

Rational vector design is pivotal for successful human gene therapy and the application of high-throughput methods may provide a means for the efficient realization of vectors with desired properties. A method involving DNA shuffling represents a powerful new paradigm in this regard.

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University of Alabama at Birmingham
United States

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