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Nature
Article
Data sources: UnpayWall
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Nature
Article . 2014 . Peer-reviewed
License: Springer Nature TDM
Data sources: Crossref
Nature
Article . 2014
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Preclinical research: Make mouse studies work

Authors: Steve, Perrin;

Preclinical research: Make mouse studies work

Abstract

More investment to characterize animal models can boost the ability of preclinical work to predict drug effects in humans, says Steve Perrin.

Keywords

Clinical Trials as Topic, Dose-Response Relationship, Drug, Superoxide Dismutase, Amyotrophic Lateral Sclerosis, Drug Evaluation, Preclinical, Reproducibility of Results, Guidelines as Topic, Survival Analysis, Translational Research, Biomedical, Disease Models, Animal, Mice, Superoxide Dismutase-1, Organ Specificity, Research Design, Cause of Death, Disease Progression, Animals, Humans, False Positive Reactions, Half-Life

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    596
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
596
Top 0.1%
Top 1%
Top 0.1%
bronze