
doi: 10.1038/4429
pmid: 9915493
The structural features of nucleic acid probes tethered to a solid support and the molecular basis of their interaction with targets in solution have direct implication for the hybridization process. We discuss how arrays of oligonucleotides provide powerful tools to study the molecular basis of these interactions on a scale which is impossible using conventional analysis.
Base Composition, Binding Sites, Base Sequence, DNA Ligases, Nucleic Acid Conformation, DNA-Directed DNA Polymerase, Oligonucleotide Probes, Base Pairing, Oligonucleotide Array Sequence Analysis
Base Composition, Binding Sites, Base Sequence, DNA Ligases, Nucleic Acid Conformation, DNA-Directed DNA Polymerase, Oligonucleotide Probes, Base Pairing, Oligonucleotide Array Sequence Analysis
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 680 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 1% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 0.1% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 0.1% |
