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Nature
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Nature
Article . 2003 . Peer-reviewed
License: Springer Nature TDM
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Nature
Article . 2003
Data sources: Europe PubMed Central
https://dx.doi.org/10.1038/422...
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Drug target validation: Hitting the target

descriptionPublicationkeyboard_double_arrow_right Article 20 Mar 2003 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 422, pages 342-345 (issn: 0028-0836, eissn: 1476-4687, Copyright policy )
Authors: Caitlin, Smith;

doi: 10.1038/422341a

pmid: 12646927

Drug target validation: Hitting the target

Abstract

The route to new therapeutics often ends in costly failure. The secret of success is the rapid and accurate identification of drug targets with true potential, says Caitlin Smith.

Keywords

Proteomics, Binding Sites, Drug Industry, Drug Evaluation, Preclinical, Reproducibility of Results, Substrate Specificity, Pharmaceutical Preparations, Animals, Humans, Computer Simulation, Gene Deletion, Software

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 39
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
39
Top 10%
Top 10%
Top 10%
bronze
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