
doi: 10.1038/355476a0
pmid: 1370860
A new process, antigenization of antibodies, consisting of the expression of oligopeptides in the hypervariable loops of an antibody molecule is described. The potential applications of antigenized antibodies are discussed.
T-Lymphocytes, Immunoglobulin Variable Region, Antigen-Antibody Complex, Antibodies, Epitopes, Mice, Mutagenesis, Insertional, CD4 Antigens, Animals, Humans, Immunoglobulin Light Chains, Binding Sites, Antibody, Antigens, Immunoglobulin Heavy Chains
T-Lymphocytes, Immunoglobulin Variable Region, Antigen-Antibody Complex, Antibodies, Epitopes, Mice, Mutagenesis, Insertional, CD4 Antigens, Animals, Humans, Immunoglobulin Light Chains, Binding Sites, Antibody, Antigens, Immunoglobulin Heavy Chains
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