New class ll-like genes in the murine MHC
Copyright policy )New class ll-like genes in the murine MHC
Major histocompatibility complex (MHC) class I molecules present endogenous antigens to CD8+ (cytotoxic) T cells. MHC class II molecules present primarily exogenously derived antigens to CD4+ T cells. Three new genes (Ma, Mb1 and Mb2) located between the Pb and Ob genes of the murine MHC have properties indicating that they are members of the MHC class II gene family, but they are the most divergent class II members so far identified and are almost as closely related in sequence to class I genes as they are to the known class II genes.
- Virginia Commonwealth University United States
- Virginia Commonwealth University Medical Center United States
Mice, Base Sequence, Genes, MHC Class II, Molecular Sequence Data, Histocompatibility Antigens Class II, Animals, Membrane Proteins, Amino Acid Sequence, Sequence Alignment
Mice, Base Sequence, Genes, MHC Class II, Molecular Sequence Data, Histocompatibility Antigens Class II, Animals, Membrane Proteins, Amino Acid Sequence, Sequence Alignment
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