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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Naturearrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Nature
Article . 1990 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Nature
Article . 1991
Data sources: Europe PubMed Central
https://dx.doi.org/10.1038/348...
Article
Data sources: Microsoft Academic Graph
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Today's SCID-hu mouse

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1990 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 348, pages 561-562 (issn: 0028-0836, eissn: 1476-4687, Copyright policy )
Authors: H, Kaneshima; C, Baum; B, Chen; R, Namikawa; H, Outzen; L, Rabin; A, Tsukamoto; +1 Authors

doi: 10.1038/348561a0

pmid: 2247165

Today's SCID-hu mouse

Abstract

Use of the SCID-hu mouse — an immunodeficient mouse transplanted with relevant organs of the human immune system — as a preclinical testing system for human therapeutics is discussed.

Keywords

Chimera, Immunity, Immunologic Deficiency Syndromes, HIV Infections, Mice, Mutant Strains, Hematopoiesis, Disease Models, Animal, Mice, Animals, Humans

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 22
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
22
Average
Top 10%
Top 10%
Related to Research communities
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