Identification of a receptor for the morphogen retinoic acid

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1987 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 330, pages 624-629 (issn: 0028-0836, eissn: 1476-4687,

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Authors: V, Giguere; E S, Ong; P, Segui; R M, Evans;

doi: 10.1038/330624a0

pmid: 2825036

Identification of a receptor for the morphogen retinoic acid

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Abstract

Analysis of complementary DNA encoding a novel gene product reveals striking similarity to the steroid and thyroid hormone receptors. Binding and transcription activational studies show it to be a receptor for the vitamin A-related morphogen retinoic acid.

Related Organizations

Salk Institute for Biological Studies
United States
Howard Hughes Medical Institute
United States

Keywords

Base Sequence, Receptors, Retinoic Acid, Molecular Sequence Data, Recombinant Proteins, DNA-Binding Proteins, Gene Expression Regulation, Genes, Multigene Family, Genes, Regulator, Morphogenesis, Amino Acid Sequence, Carrier Proteins, Transcription Factors

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