Single-channel currents of an intercellular junction

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1985 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 317, pages 331-335 (issn: 0028-0836, eissn: 1476-4687,

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Authors: J, Neyton; A, Trautmann;

doi: 10.1038/317331a0

pmid: 2413362

Single-channel currents of an intercellular junction

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Abstract

We have used a double whole-cell patch-clamp system to make the first quantitative recordings of the single-channel current from an intercellular junction, presumably a gap junction. The junctional channel has various conductance states and discriminates poorly between cations and anions. It seems to change slowly from one conductance state to another.

Related Organizations

École Normale Supérieure
France

Keywords

Ions, Kinetics, Intercellular Junctions, Lacrimal Apparatus, Animals, Models, Biological, Ion Channels, Membrane Potentials, Rats

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