Dynamic instability of microtubule growth

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1984 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 312, pages 237-242 (issn: 0028-0836, eissn: 1476-4687,

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Authors: T, Mitchison; M, Kirschner;

doi: 10.1038/312237a0

pmid: 6504138

Dynamic instability of microtubule growth

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Abstract

We report here that microtubules in vitro coexist in growing and shrinking populations which interconvert rather infrequently. This dynamic instability is a general property of microtubules and may be fundamental in explaining cellular microtubule organization.

Related Organizations

University of California, San Francisco
United States

Keywords

Kinetics, Mice, Cell-Free System, Polymers, Tubulin, Animals, Microtubules, Protein Binding

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