Calmodulin—an intracellular calcium receptor

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1980 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 285, pages 73-77 (issn: 0028-0836, eissn: 1476-4687,

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Authors: A R, Means; J R, Dedman;

doi: 10.1038/285073a0

pmid: 6990273

Calmodulin—an intracellular calcium receptor

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Abstract

Calmodulin, a protein that binds calcium with high affinity and specificity, is structurally conserved and functionally preserved throughout the animal and plant kingdoms. It serves as an intracellular Ca2+-receptor and mediates the Ca2+ regulation of cyclic nucleotide and glycogen metabolism, secretion, motility and Ca2+ transport. Calmodulin is also a dynamic component of the mitotic apparatus.

Related Organizations

Baylor College of Medicine
United States

Keywords

Receptors, Drug, Calcium-Binding Proteins, Mitosis, Biological Evolution, Microtubules, Troponin, Calmodulin, Tubulin, Antibody Formation, Animals, Tissue Distribution, Interphase, Protein Kinases

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