The biochemistry of complement

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1978 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 275, pages 699-704 (issn: 0028-0836, eissn: 1476-4687,

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Authors: R R, Porter; K B, Reid;

doi: 10.1038/275699a0

pmid: 703835

The biochemistry of complement

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Abstract

Current biochemical studies of the complement system are illustrated by description of the activation of complement by the classical pathway after interaction with antibody aggregates. This is described in terms of the structures of the components involved, their assembly and the mechanism of activation.

Related Organizations

University of Oxford
United Kingdom

Keywords

Complement Activating Enzymes, Protein Conformation, Hydrolysis, Complement C5, Complement C4, Antigen-Antibody Complex, Complement C3-C5 Convertases, Complement System Proteins, Complement C2, Models, Biological, Molecular Weight, Structure-Activity Relationship, Complement C1, Vertebrates, Animals, Amino Acid Sequence, Complement Activation, Protein Binding

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