Analogies between embryonic (T/t) antigens and adult major histocompatibility (H-2) antigens

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1975 United States English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 256, pages 545-547 (issn: 0028-0836, eissn: 1476-4687,

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Authors: Artzt, K; Bennett, D;

doi: 10.1038/256545a0

pmid: 1172603

Analogies between embryonic (T/t) antigens and adult major histocompatibility (H-2) antigens

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Abstract

Progress has been made in defining cell surface components specified by the T/t locus in the mouse, both in their expression on sperm and, in the one case studied, on normal embryonic cells and teratocarcinoma. Some striking analogies between this putative embryonic cell recognition system and the adult major histocompatibility complex are presented.

Country

United States

Related Organizations

Cornell University
United States
Jackson Laboratory
United States

Keywords

Serology: Antigen, Male, T locus - Talleles, Genotype, Genetic Linkage, Gestational Age, Cell Line, Mice, Histocompatibility Antigens, Animals, Antigens, Genes: H-2 - Histocompatibility-2, T brachyury, Unknown:, Physiology:, Cell Membrane, Teratoma, Chromosome Mapping, Cell Differentiation, Embryo, Mammalian, Spermatozoa, Genes, Hereditary Factors:

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