Multiple conformations of ribosomal precursor RNA

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1975 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 253, pages 282-284 (issn: 0028-0836, eissn: 1476-4687,

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Authors: J M, Slack; M L, Sartirana; U E, Loening;

doi: 10.1038/253282a0

pmid: 1113847

Multiple conformations of ribosomal precursor RNA

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Abstract

WE wish to propose an explanation for the heterogeneity shown1 by ribosomal precursor RNAs on gel electrophoresis. The clearest demonstration of this phenomenon is shown in Fig. 1. 32P-labelled RNA was eluted from single gel slices taken across the peak, and rerun in the presence of 3H-labelled marker. The 32P-RNA samples run in their original positions and not coincidentally with the marker, that is, the width of the peak does not result from diffusion alone.

Related Organizations

University of Edinburgh
United Kingdom

Keywords

Molecular Weight, Base Sequence, RNA, Ribosomal, Nucleic Acid Conformation, Nucleic Acid Denaturation

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