Active Transport of Lysergic Acid Diethylamide
Copyright policy )Active Transport of Lysergic Acid Diethylamide
ALTHOUGH it is recognized that there is little hindrance to the passage of lysergic acid diethylamide (LSD) across the blood brain barrier1, an autoradiographic study of LSD distribution in the rat brain led to speculation that the choroid plexuses are involved in the active transport of this compound between blood and cerebrospinal fluid2. It was also suggested that this tissue acts as a storage site for LSD in the brain. The purpose of this communication is to elucidate the mechanism of LSD accumulation within the choroid plexus, and clarify the role of the choroidal epithelium in the distribution of LSD between blood and brain.
- University of California, Los Angeles United States
- University of California Davis Medical Center United States
Male, Cyanides, Decamethonium Compounds, Temperature, Biological Transport, Active, Iodoacetates, In Vitro Techniques, Tritium, Kinetics, Lysergic Acid Diethylamide, Blood-Brain Barrier, Choroid Plexus, Animals, Chromatography, Thin Layer, Anura, Ouabain
Male, Cyanides, Decamethonium Compounds, Temperature, Biological Transport, Active, Iodoacetates, In Vitro Techniques, Tritium, Kinetics, Lysergic Acid Diethylamide, Blood-Brain Barrier, Choroid Plexus, Animals, Chromatography, Thin Layer, Anura, Ouabain
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