Effect of Temperature on the Equilibrium Endplate Potential

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1972 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 236, pages 453-454 (issn: 0028-0836, eissn: 1476-4687,

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Authors: P D, Bregestovski; L M, Chailachjan; V L, Dunin-Barkovski; T W, Potapova; B N, Veprintsev;

doi: 10.1038/236453a0

pmid: 4555361

Effect of Temperature on the Equilibrium Endplate Potential

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Abstract

IT has been suggested1 that during the interaction of acetylcholine (ACh) with the cholinergic receptor (ChR) each elementary ionic channel of the postsynaptic membrane (PSM) becomes active, that is accessible for K+ and Na+ ions, for such short a time that the equilibrium potential (Ep) of PSM is determined by a current which is far from stationary. This suggestion—the hypothesis2 of “transient state of ionic channel”—arose from the finding3,4 that Ep of the PSM is described by in wide range of external concentrations of K+ and Na+ ions, where [K]o, [Na]o, and [K]i, [Na]i are the external and internal K+ and Na+ concentrations respectively; ΔgK and ΔgNa are PSM conductances for K+ and Na+ ions respectively; R is the gas constant, F is the Faraday number and T is theabsolute temperature.

Related Organizations

Russian Academy of Sciences
Russian Federation

Keywords

Cold Temperature, Cell Membrane Permeability, Hot Temperature, Rana temporaria, Neuromuscular Junction, Temperature, Animals, Anura, In Vitro Techniques, Membrane Potentials

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