THE question of how skin grafts are revascularized is still not resolved1–3. In particular, it is not known whether the vessels in the vascular bed of a graft derive from the host or the donor. In what follows, we provide three independent lines of evidence which suggest that in full-thickness skin grafts, the vessels are native to the graft at least for the first several days and during the period of allograft rejection. The possibility that the endothelium in surviving allografts may eventually be replaced by cells of host genotype is important4 but outside the scope of this report.